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By dr_mattbarrett

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5 days ago

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dr_mattbarrett Sound Effects

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⚠️ Tap here for the answer! ✅ Spoiler alert: Jaundice Here we can see jaundice of the skin - characterised by deposition of the yellow pigment bilirubin in the tissues. Bilirubin is the breakdown product of heme (in haemoglobin) We can’t possibly say the cause with such limited information but we can categorise jaundice as follows: 🩸Pre hepatic: excess haemolysis/abnormal conjugation - haemolytic anaemia - Malaria - Gilbert’s syndrome - Criggler-Najjar 🍺 Intrahepatic: hepatocellular dysfunction - Hepatitis (viral/ischaemic/toxic) - Alcoholic liver disease - Haemochromatosis - Autoimmune hepatitis 🤚Post hepatic: Abnormal drainage of bile through the biliary system - pancreatic cancer - Cholangiocarcinoma - Primary biliary cirrhosis - Primary sclerosis cholangitis 💡 Asymptomatic jaundice during an acute illness? Consider Gilbert’s disease. 💡 Jaundice in the context of excess alcohol? Think Alcoholic liver disease 💡 Jaundice in the context of T2DM? Think non-alcoholic fatty liver disease. #medical #doctor #medico #nurse #mbbs
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